Causes of Nephrotic Syndrome (NS)
Systemic Causes | Glomerular Disease |
---|---|
Diabetes mellitus, SLE, amyloidosis, HIV-associated nephropathy | Membranous Minimal change disease |
Drugs: gold, penicillamine, probenecid, street heroin, NSAIDs, pamidronate, interferons | Focal glomerulosclerosis |
Infections: bacterial endocarditis, hepatitis B, shunt infections, syphilis, malaria, hepatic schistosomiasis | Membranoproliferative GN |
Malignancy: multiple myeloma, light chain deposition disease, Hodgkin's and other lymphomas, leukemia, carcinoma of breast and GI tract | Mesangioproliferative GN Immunotactoid and fibrillary GN |
Abbreviations: GN, glomerulonephritis.
Source: Modified from RJ Glassock, BM Brenner: HPIM-13.