Causes of Ischemic Stroke
Common Causes | Uncommon Causes |
---|---|
Thrombosis Lacunar stroke (small vessel) Large-vessel thrombosis Dehydration Embolic occlusion Artery-to-artery Carotid bifurcation Aortic arch Arterial dissection Cardioembolic Atrial fibrillation Mural thrombus Myocardial infarction Dilated cardiomyopathy Valvular lesions Mitral stenosis Mechanical valve Bacterial endocarditis Paradoxical embolus Atrial septal defect Patent foramen ovale Atrial septal aneurysm Spontaneous echo contrast Stimulant drugs: cocaine, amphetamine | Hypercoagulable disorders Protein C deficiencya Protein S deficiencya Antithrombin III deficiencya Antiphospholipid syndrome Factor V Leiden mutationa Prothrombin G20210 mutationa Systemic malignancy Sickle cell anemia β Thalassemia Polycythemia vera Systemic lupus erythematosus Homocysteinemia Thrombotic thrombocytopenic purpura Disseminated intravascular coagulation Dysproteinemiasa Nephrotic syndromea Inflammatory bowel diseasea Oral contraceptives Venous sinus thrombosisb Fibromuscular dysplasia Vasculitis Systemic vasculitis (PAN, granulomatosis with polyangiitis [Wegener's], Takayasu's, giant cell arteritis) Primary CNS vasculitis Meningitis (syphilis, tuberculosis, fungal, bacterial, zoster) Noninflammatory vasculopathy Reversible vasoconstriction syndrome Fabry's disease Angiocentric lymphoma Cardiogenic Mitral valve calcification Atrial myxoma Intracardiac tumor Marantic endocarditis Libman-Sacks endocarditis Subarachnoid hemorrhage vasospasm Moyamoya disease Eclampsia |
aChiefly cause venous sinus thrombosis.
bMay be associated with any hypercoagulable disorder.
Abbreviations: PAN, polyarteritis nodosa.