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Table 49-2

Headache Symptoms that Suggest A Serious Underlying Disorder

Sudden-onset headache
First severe headache
“Worst” headache ever
Vomiting that precedes headache
Subacute worsening over days or weeks
Pain induced by bending, lifting, cough
Pain that disturbs sleep or presents immediately upon awakening
Known systemic illness
Onset after age 55 years
Fever or unexplained systemic signs
Abnormal neurologic examination
Pain associated with local tenderness, e.g., region of temporal artery