section name header

Table 65-4

International Prognostic Scoring System (IPSS)

Prognostic Variable Score Value
00.511.52
Bone marrow blasts (%)<5%5-10% 11-20%21-30%
KaryotypeaGoodIntermediatePoor
Cytopeniab (lineages affected)0 or 12 or 3
Risk Group ScoresScore
Low0
Intermediate-10.5-1
Intermediate-21.5-2
High2.5

aGood, normal, -Y, del(5q), del(20q); poor, complex (3 abnormalities) or chromosome 7 abnormalities; intermediate, all other abnormalities.

bCytopenias defined as Hb <100 g/L, platelet count <100,000/µL, absolute neutrophil count <1500/µL.