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Table 154-4

Indications for Liver Transplantation

ChildrenAdults
Biliary atresiaPrimary biliary cirrhosis
Neonatal hepatitisSecondary biliary cirrhosis
Congenital hepatic fibrosisPrimary sclerosing cholangitis
Alagille syndromeaAutoimmune hepatitis
Byler diseasebCaroli diseasec
α1-Antitrypsin deficiencyCryptogenic cirrhosis
Inherited disorders of metabolismChronic hepatitis with cirrhosis
Wilson's diseaseHepatic vein thrombosis
TyrosinemiaFulminant hepatitis
Glycogen storage diseasesAlcoholic cirrhosis
Lysosomal storage diseasesChronic viral hepatitis
ProtoporphyriaPrimary hepatocellular malignancies
Crigler-Najjar disease type IHepatic adenomas
Familial hypercholesterolemiaNonalcoholic steatohepatitis
Primary hyperoxaluria type IFamilial amyloid polyneuropathy
Hemophilia

aArteriohepatic dysplasia, with paucity of bile ducts, and congenital malformations, including pulmonary stenosis.

bIntrahepatic cholestasis, progressive liver failure, mental and growth retardation.

cMultiple cystic dilatations of the intrahepatic biliary tree.