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Table 36-1

Causes of Cyanosis

Central Cyanosis
Decreased arterial oxygen saturation
Decreased atmospheric pressure-high altitude
Impaired pulmonary function
 Alveolar hypoventilation
 Inhomogeneity in pulmonary ventilation and perfusion (perfusion of hypoventilated alveoli)
 Impaired oxygen diffusion
Anatomic shunts
 Certain types of congenital heart disease
 Pulmonary arteriovenous fistulas
 Multiple small intrapulmonary shunts
Hemoglobin with low affinity for oxygen
Hemoglobin abnormalities
 Methemoglobinemia-hereditary, acquired
 Sulfhemoglobinemia-acquired
 Carboxyhemoglobinemia (not true cyanosis)
Peripheral Cyanosis
Reduced cardiac output
Cold exposure
Redistribution of blood flow from extremities
Arterial obstruction
Venous obstruction