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Table 128-1

Classification of Raynaud's Phenomenon

Primary or idiopathic Raynaud's phenomenon: Raynaud's disease

Secondary Raynaud's phenomenon

Collagen vascular diseases: scleroderma, systemic lupus erythematosus, rheumatoid arthritis, dermatomyositis, polymyositis, Sjögren's syndrome

Arterial occlusive diseases: atherosclerosis of the extremities, thromboangiitis obliterans, acute arterial occlusion, thoracic outlet syndrome

Pulmonary hypertension

Neurologic disorders: intervertebral disk disease, syringomyelia, spinal cord tumors, stroke, poliomyelitis, carpal tunnel syndrome

Blood dyscrasias: cold agglutinins, cryoglobulinemia, cryofibrinogenemia, myeloproliferative disorders, lymphoplasmacytic lymphoma

Trauma: vibration injury, hammer hand syndrome, electric shock, cold injury, typing, piano playing

Drugs: ergot derivatives, methysergide, β-adrenergic receptor blockers, bleomycin, vinblastine, cisplatin, gemcitabine