Contraindications to Renal Transplantation

Contraindications to Renal Transplantation
Absolute Contraindications
Active glomerulonephritis
Active bacterial or other infection
Active or very recent malignancy
Overt AIDS^a
Active hepatitis
Severe degrees of comorbidity (e.g., advanced atherosclerotic vascular disease)
Relative Contraindications
Severe psychiatric disease
Moderately severe degrees of comorbidity
Hepatitis C infection with chronic hepatitis or cirrhosis
Noncompliance with dialysis or other medical therapy
Primary renal diseases
Primary focal sclerosis with prior recurrence in transplant
Multiple myeloma
Amyloid
Oxalosis

^a Most centers consider overt AIDS a contraindication to transplantation; however, transplantation of HIV-positive pts is increasing in frequency.