Causes of Elevated Cardiac Troponin Reflecting Direct Myocardial Damage Other Than Spontaneous Myocardial Infarction (Type 1) | |
CARDIAC | NON-CARDIAC OR SYSTEMIC |
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Tachyarrhythmias Congestive heart failure Hypertensive emergencies Infection/inflammation (e.g., myocarditis, pericarditis) Stress cardiomyopathy (Tako-Tsubo cardiomyopathy) Structural heart disease (e.g., aortic stenosis) Aortic dissection Coronary spasm Cardiac procedures (endomyocardial biopsy, ablation, CABG, PCI) Infiltrative diseases (e.g., amyloidosis, hemochromatosis, malignancy) | Pulmonary embolism/pulmonary hypertension Trauma (e.g., electrical shock, burns, blunt chest wall) Hypo or hyperthyroidism Toxicity (e.g., anthracyclines, snake venom) Renal failure Sepsis, shock Stroke or other acute neurologic event Extreme endurance efforts (e.g., ultra-marathon) Rhabdomyolysis |