Comparison of Seventh and Eight Edition TNM Staging Systems for Non-Small-Cell Lung Cancer | ||
| TNM STAGING SYSTEM FOR LUNG CANCER (7TH EDITION) | TNM STAGING SYSTEM FOR LUNG CANCER (8TH EDITION) | |
|---|---|---|
| Primary tumor (T) | ||
| T1 | Tumor ≤3 cm diameter, surrounded by lung or visceral pleura, without invasion more proximal than lobar bronchus | T1 tumor ≤3 cm in diameter surrounds by lung or visceral pleural without evidence of main bronchus |
| T1a | Tumor ≤2 cm in diameter | Tumor <1 cm |
| T1b | Tumor >2 cm but ≤3 cm in diameter | Tumor ≥1 cm but ≤2 cm |
| T1c | N/A | Tumor >2 cm but ≤3 cm |
| T2 | Tumor >3 cm but ≤7 cm, or tumor with any of the following features: | T2 tumor >3 cm but ≤5 cm or tumor with any of the following features that does not involve the entire lung |
| Involves main bronchus ≥2 cm distal to carina | Involves main bronchus ≥2 cm distal to carina | |
| Invades visceral pleura | Invades visceral pleura | |
| Associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung | Associate with atelectasis or obstructive pneumonitis that extends to the hilar region | |
| T2a | Tumor >3 cm but ≤5 cm | Tumor >3 cm but ≤4 cm |
| T2b | Tumor >5 cm but ≤7 cm | Tumor >4 cm but ≤5 cm |
| T3 | Tumor >7 cm or any of the following: | >5 cm but ≤7 cm or any of the following: |
| Directly invades any of the following: chest wall, diaphragm, phrenic nerve, mediastinal pleura, parietal pericardium, main bronchus <2 cm from carina (without involvement of carina) | Directly invades any of the following chest wall, diaphragm, phrenic nerve, mediastinal pleura, parietal pericardium, main bronchus <2 cm from carina (without involvement of carina) | |
| Atelectasis or obstructive pneumonitis of the entire lung | Atelectasis or obstructive pneumonitis of the entire lung | |
| Separate tumor nodules in the same lobe | ||
| T4 | Tumor of any size that invades the mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina, or with separate tumor nodules in a different ipsilateral lobe | 7 cm or any of the following invades the mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina, or with separate tumor nodules in a different ipsilateral lobe |
| Regional lymph nodes (N) | ||
| N0 | No regional lymph node metastases | N0 No regional lymph node metastases |
| N1 | Metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension | N1 Metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension |
| N2 | Metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s) | N2 Metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s) |
| N3 | Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s) | N3 Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s) |
| Distant metastasis (M) | ||
| M0 | No distant metastasis | M0 No distant metastasis |
| M1 | Distant metastasis | Distant metastasis |
| M1a | Separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules or malignant pleural or pericardial effusion | M1 a separate nodule(s) in a contralateral tumor with pleural nodules or malignant pleural or pericardial effusion |
| M1b | Distant metastasis (in extrathoracic organs) | Single metastasis in a single organ |
| M1c | multiple metastases in a single organ or in several organs | |