Algorithm for Evaluating the Thrombocytopenic Pt - Flowchart
Algorithm for Evaluating the Thrombocytopenic Pt - Flowchart
«Flowchart»

ALGORITHM FOR THROMBOCYTOPENIA EVALUATION

Platelet count <150,000/µL

ALGORITHM FOR THROMBOCYTOPENIA EVALUATION

Platelet count <150,000/µL

ALGORITHM FOR THROMBOCYTOPENIA EVALUATION

ALGORITHM FOR THROMBOCYTOPENIA EVALUATION

Platelet count <150,000/µL

End

End

End

DIC, disseminated intravascular coagulation; RBC, red blood cell; TTP, thrombotic thrombocytopenic purpura.

DIC, disseminated intravascular coagulation; RBC, red blood cell; TTP, thrombotic thrombocytopenic purpura.

DIC, disseminated intravascular coagulation; RBC, red blood cell; TTP, thrombotic thrombocytopenic purpura.

Hemoglobin and white blood count

Hemoglobin and white blood count

Hemoglobin and white blood count

Normal

Normal

Normal

Abnormal

Abnormal

Abnormal

Bone marrow examination

Bone marrow examination

Bone marrow examination

Consider:
Drug-induced thrombocytopenia
Infection-induced thrombocytopenia
Idiopathic immune thrombocytopenia
Congenital thrombocytopenia

Consider:
Drug-induced thrombocytopenia
Infection-induced thrombocytopenia
Idiopathic immune thrombocytopenia
Congenital thrombocytopenia

Consider:
Drug-induced thrombocytopenia
Infection-induced thrombocytopenia
Idiopathic immune thrombocytopenia
Congenital thrombocytopenia





Microangiopathic hemolytic anemias (e.g., DIC, TTP)

Microangiopathic hemolytic anemias (e.g., DIC, TTP)

Microangiopathic hemolytic anemias (e.g., DIC, TTP)

Peripheral blood smear

Peripheral blood smear

Peripheral blood smear

Normal RBC morphology; platelets normal or increased in size

Normal RBC morphology; platelets normal or increased in size

Normal RBC morphology

Fragmented red blood cells

Fragmented red blood cells

Fragmented red blood cells

Platelets clumped: redraw in sodium citrate or heparin

Platelets clumped: redraw in sodium citrate or heparin

Platelets clumped