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Table 67-3

Follicular Lymphoma International Prognostic Index-2 (FLIPI-2)

Five clinical risk factors:

Age >60 years

Serum β2-microglobulin increased

Hemoglobin <12 gm/dL

Bone marrow involvement

Longest diameter of largest node >6 cm

0 factor = low risk:5-year progression-free survival 76-80%
1-2 factors = intermediate risk:5-year progression-free survival 49-51%
3-5 factors = high risk:5-year progression-free survival 20-37%