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Table 157-4

Indications for Liver Transplantation

CHILDRENADULTS
Biliary atresiaPrimary biliary cirrhosis
Neonatal hepatitisSecondary biliary cirrhosis
Congenital hepatic fibrosisPrimary sclerosing cholangitis
Alagille's syndromea Autoimmune hepatitis
Byler's diseaseb Caroli's diseasec
α1-Antitrypsin deficiencyCryptogenic cirrhosis
Inherited disorders of metabolismChronic hepatitis with cirrhosis
 Wilson's diseaseHepatic vein thrombosis
 TyrosinemiaFulminant hepatitis
 Glycogen storage diseasesAlcoholic cirrhosis
 Lysosomal storage diseasesChronic viral hepatitis
 ProtoporphyriaPrimary hepatocellular malignancies
 Crigler-Najjar disease type IHepatic adenomas
 Familial hypercholesterolemiaNonalcoholic steatohepatitis
 Primary hyperoxaluria type IFamilial amyloid polyneuropathy
 Hemophilia

aArteriohepatic dysplasia, with paucity of bile ducts, and congenital malformations, including pulmonary stenosis.

bIntrahepatic cholestasis, progressive liver failure, and mental and growth retardation.

cMultiple cystic dilatations of the intrahepatic biliary tree.