Contraindications to Liver Transplantation | |
| ABSOLUTE | RELATIVE |
|---|---|
| Uncontrolled extrahepatobiliary infection | Age >70 |
| Active, untreated sepsis | Prior extensive hepatobiliary surgery |
| Uncorrectable, life-limiting congenital anomalies | Portal vein thrombosis |
| Active substance or alcohol abuse | Renal failure not attributable to liver disease |
| Advanced cardiopulmonary disease | Previous extrahepatic malignancy (not including nonmelanoma skin cancer) |
| Extrahepatobiliary malignancy (not including nonmelanoma malignancy skin cancer) | Severe obesity |
| Metastatic malignancy to the liver | Severe malnutrition/wasting |
| Cholangiocarcinoma | Medical noncompliance |
| AIDS | HIV seropositivity with failure to control HIV viremia or CD4 <100/µL |
| Life-threatening systemic diseases | Intrahepatic sepsis |
Severe hypoxemia secondary to right-to-left intrapulmonary shunts (PO2<50 mmHg) | |
| Severe pulmonary hypertension (mean pulmonary artery pressure >35 mmHg) | |
| Uncontrolled psychiatric disorder | |