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Table 53-2

Treatment of Vertigo

AGENTa DOSEb
Antihistamines
Meclizine25-50 mg 3 times daily
Dimenhydrinate50 mg 1-2 times daily
Promethazine25 mg 2-3 times daily (also can be given rectally and IM)
Benzodiazepines
Diazepam2.5 mg 1-3 times daily
Clonazepam0.25 mg 1-3 times daily
Anticholinergic
Scopolamine transdermalc Patch
Physical therapy
Repositioning maneuversd
Vestibular rehabilitation
Other
Diuretics and/or low-sodium (1000 mg/d) diete
Antimigrainous drugsf
Methylprednisoloneg100 mg daily days 1-3; 80 mg daily days 4-6; 60 mg daily days 7-9; 40 mg daily days 10-12; 20 mg daily days 13-15; 10 mg daily days 16-18, 20, 22
Selective serotonin reuptake inhibitorsh

a All listed drugs are approved by the U.S. Food and Drug Administration, but most are not approved for the treatment of vertigo.

b Usual oral (unless otherwise stated) starting dose in adults; a higher maintenance dose can be reached by a gradual increase.

c For motion sickness only.

d For benign paroxysmal positional vertigo.

e For Ménière's disease.

f For vestibular migraine.

g For acute vestibular neuritis (started within 3 days of onset).

h For persistent postural-perceptual vertigo and anxiety.