section name header

Table 79-1

Paraneoplastic Syndromes of the Nervous System

CLASSIC SYNDROMES: USUALLY OCCUR WITH CANCER ASSOCIATIONNONCLASSIC SYNDROMES: MAY OCCUR WITH AND WITHOUT CANCER ASSOCIATION

Encephalomyelitis

Limbic encephalitis

Cerebellar degeneration (adults)

Opsoclonus-myoclonus

Subacute sensory neuronopathy

Gastrointestinal paresis or pseudo-obstruction

Dermatomyositis (adults)

Lambert-Eaton myasthenic syndrome

Cancer- or melanoma-associated retinopathy

Brainstem encephalitis

Stiff-person syndrome

Progressive encephalomyelitis with rigidity and myoclonus

Necrotizing myelopathy

Motor neuron disease

Guillain-Barré syndrome

Subacute and chronic mixed sensory-motor neuropathies

Neuropathy associated with plasma cell dyscrasias and lymphoma

Vasculitis of nerve

Pure autonomic neuropathy

Acute necrotizing myopathy

Polymyositis

Optic neuropathy

BDUMP

Peripheral nerve hyperexcitability (neuromyotonia)

Myasthenia gravis

Abbreviation: BDUMP, bilateral diffuse uveal melanocytic proliferation.