Initial Combination Regimens Recommended for Most Treatment-Naïve Pts Regardless of HIV RNA Level or CD4 Count | |||
Dolutegravir + tenofovir* + emtricitabine** Raltegravir + tenofovir* + emtricitabine** Bictegravir + tenofovir* + emtricitabine** Elvitegravir + cobicistat + tenofovir* + emtricitabine** Dolutegravir + abacavir + lamivudine** (only for those HLA-B*5701 negative) |
* Tenofovir alafenamide and tenofovir disoproxil fumarate are two forms of tenofovir approved by FDA. Tenofovir alafenamide has fewer bone and renal toxicities while tenofovir disoproxil fumarate is associated with lower lipid levels.
**Lamivudine may substitute for emtricitabine and vice versa.
Source: Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents, USPHS.