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Figure 159-1

Bioactive Mediators of Three Categories Generated by Ige-Dependent Activation of Murine Mast Cells Can Elicit Common but Sequential Target Cell Effects Leading to Acute and Sustained Inflammatory Responses

Bioactive mediators of three categories generated by IgE-dependent activation of murine mast cells can elicit common but sequential target cell effects leading to acute and sustained inflammatory responses. GM-CSF, granulocyte-macrophage colony-stimulating factor; IFN, interferon; IL, interleukin; LT, leukotriene; PAF, platelet-activating factor; PGD2, prostaglandin D2; TNF, tumor necrosis factor.