- Women aged ≥65 and men aged ≥70; regardless of clinical risk factors
- Younger postmenopausal women, women in the menopausal transition, and men aged 50-69 with clinical risk factors for fracture
- Adults who have a fracture at or after age 50
- Adults with a condition (e.g., rheumatoid arthritis) or taking a medication (e.g., glucocorticoids at a daily dose >5 mg prednisone or equivalent for >3 months associated with low bone mass or bone loss)
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