Cerebral Perfusion Pressure (CPP)
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Mean Art Pres (mmHg)
CVP/ICP (mmHg)
R e s u l t s
CPP (mmHg)
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Cerebral Perfusion Pressure (CPP)

The cerebral perfusion pressure (CPP) refers to the net vascular pressure gradient required for maintenance of cerebral perfusion. The normal range for CPP is 70-85 mmHg.

It is essential to maintain an optimal CPP to ensure a sufficient supply of blood and oxygen to fulfill the metabolic requirements of the brain.

A poor CPP increases the risk of cerebral ischemia. Traumatic brain injuries are the most common cause of a reduced CPP.

Formula used:

CPP = MAP - ICP

OR

CPP = MAP - CVP

Data the user will need:

  • Mean arterial pressure (MAP); units are mmHg
  • Intracranial pressure (ICP); units are mmHg
  • Central venous pressure (CVP); units are mmHg

Abbreviations used:

  • CPP = Cerebral perfusion pressure
  • CVP = Central venous pressure
  • ICP = Intracranial pressure
  • MAP = Mean arterial pressure

Interpretation:

User need to enter the above mentioned values, which are used in the formulas given below

CPP = MAP - ICP

OR

CPP = MAP - CVP

References:

Rosner MJ, Daughton S. Cerebral perfusion pressure management in head injury. J Trauma. 1990;30(8):933-40.

Vespa P. What is the optimal threshold for cerebral perfusion pressure following traumatic brain injury?. Neurosurg Focus. 2003;15(6):E4.