No. Needed to Treat
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Ctrl.Gr. (Total)
Ctrl.Gr. (w/ Cond)
Act.Tx Grp. (Total)
Act.Tx Grp. (w/ Cond)
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No. needed to treat
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No. Needed to Treat

It is a statistics equation used to calculate the number of patient a clinician need to treat with a particular therapy to prevent adverse outcome

No. Needed to Treat = The number of patients you need to treat in order to prevent condition

1 ÷ ((Ctrl.Gr.(w/ Cond) ÷ Ctrl.Gr.(Total)) - (Act.Tx Gr.(w/ Cond) ÷ Act.Tx Gr.(Total))

Ctrl.Gr.(Total) = Number of People in Control Group

Ctrl.Gr.(w/ Cond) = Number of People in Control Group who develop condition of interest during time interval

Act.Tx Gr.(Total) = Number of People in Active Treatment Group

Act.Tx Gr.(w/ Cond) = Number of People in Active Treatment Group who develop condition of interest during time interval

References:

  1. Cook RJ, Sackett DL.The number needed to treat: a clinically useful measure of treatment effect. BMJ . 1995;310(6977):452-4.
  2. Chatellier G, ZapletalE, Lemaitre D, Menard J, Degoulet P. The number needed to treat: a clinically useful nomogram in its proper context BMJ 1996; 312:426 - 42.