No tenderness at the posterior midline of the cervical spine | Yes No |
No focal neurologic deficit | Yes No |
Normal level of alertness | Yes No |
No evidence of intoxication | Yes No |
No clinically apparent painful distracting injury | Yes No |
Cervical radiography following blunt trauma is extremely common. However, eliminating unnecessary radiographs by clinical criteria is recommended in appropriate cases.
The National Emergency X-Radiography Utilization Study (NEXUS) was a major study used to validate this set of criteria and tested prospectively that patients who meet all 5 criteria listed below have very low probability of "clinically significant injury to the cervical spine."
The study by Hoffman et al., involved 21 centers, with 34,069 patients who received C-spine radiography following blunt trauma. These criteria identified all but 8 of the 818 patients who had cervical spine injury. Sensitivity was 99.0% and negative predictive value of 99.8%.
The 5 criteria
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