Nasal Canula Fio(2) Estimate
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Standard Nasal Canula 0.5 L/min 1L/min 1.5 L/min 2 L/min 2.5 L/min 3 L/min 3.5 L/min 4 L/min 4.5 L/min 5 L/min 5.5 L/min 6 L/min -
High Flow Nasal Canula 6 L/min 8 L/min 10 L/min 12 L/min 15 L/min -
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Nasal Canula Fio(2) Estimate

This information below applies to ADULTS ONLY

Oxygen supplementation by nasal canula (NC) is common; and estimation of the inspired fraction of oxygen various flow rates generate can be useful when interpreting ABG data or response to oxygen.

Room air is 21% oxygen and the addition of each 1 liter/minute (L/min) flow rate by nasal canula typically raises the FIO 2 by 3%.

Est. FiO 2 = 21% + L/min x 3%

Flow rates at maximum 6 L/min are recommended by NC.

However, in recent times; High Flow Nasal Canulas (HFNC) have become available that allow much higher flow rates, including up to 15 lpm to be used. It is notable, that although the same FiO 2 can be achieved with HFNC as simple masks (SM) or non-rebreather masks (NRM); the variability in actual FiO 2 is much greater with these devices (as it likely is with a standard NC).

O 2 Flow in liters/min FiO 2 % mean Range FiO 2 %
6 54% 35-89%
8 58% 33-87%
10 66% 40-88%
12 69% 37-93%
15 75% 39-98%

Garcia JA, et al. The Oxygen Concentrations Delivered by Different Oxygen Therapy Systems. Chest. 2005;128(4):389S.