Urea Reduction % (Hemodialysis)
Info
Urea pre Hemodialysis
unit mg/dL mmol/L
Urea post Hemodialysis
unit mg/dL mmol/L
R e s u l t s
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Info
Urea Reduction % (Hemodialysis)

Hemodialysis is a life-sustaining procedure for the treatment of patients with end-stage renal disease. A Hemodialysis dose is worked out for patients by comparing the levels of waste such as urea or creatinine in the patient's blood.

Urea Reduction percentage is a way of comparing urea levels in the blood before and after dialysis.

The formula used is:

PRU = ((UPreHD - UPostHD) / UPreHD) * 100%

Where
uprehd = Urea pre hemodialysis
UPostHD = Urea post Hemodialysis
PRU = Urea Reduction Percentage (%)

* Note units must match to be either mg/dL or mmol/L for both the urea pre and post dialysis.

This information helps interpreting adjustments to be made for future Hemodialysis sessions.

Interpretation:

Urea Reduction Percentage should be >65% per session.

References:

  • Owen WF, Lew NL, Liu Y, et al. The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med. 1993;329(14):1001-6.
  • Daugirdas JT. Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error. J Am Soc Nephrol. 1993;4(5):1205-13.