Malar Rash (Red rash of cheeks/nasal bridge) | Yes No |
Discoid rash (Red scaly rash on face, scalp, ears, arms or chest; may have atrophic scarring) | Yes No |
Photosensitivity (Reaction to sunlight resulting in skin rash) | Yes No |
Oral/Nasal ulcers (Small ulcers on mucosal linings of nose or mouth, usually painless) | Yes No |
Arthritis (Joint pain in the hands, arms, shoulders, hips, legs, feet or jaw; may be migratory and may see a warm, swollen and red joint, is nonerosive and should involve 2 or more joints) | Yes No |
Serositis (Pleurisy, pericarditis, or peritonitis (aseptic)) | Yes No |
Renal (Proteinuria and/or cellular casts in the urine: > 0.5 grams of urinary protein/day or > 3+ protein on dip stick) | Yes No |
Neurologic (Seizure or psychosis) | Yes No |
Hematologic abnormalities (Anemia (hemolytic), WBC<4000 cells/mm3, platelets<100,000 cells/mm3, or lymphocytes <1500 cells/mm3) | Yes No |
Immunologic test findings (Positive result on anti-DNA test, anticardiolipin antibodies (IgG or IgM), lupus anticoagulant, anti-Sm, or false positive VRDL known to be positive for at least 6 months and confirmed by Treponema pallidum immobilization or FTA absorption testing)) | Yes No |
Antinuclear antibody positive (Positive in the absence of drugs known to induce a positive result) | Yes No |
These criteria are from the American Rheumatism Association for Systemic Lupus Erythematosis (SLE), Revised 1997. Of 11 criteria, at least 4 should be present (do not need to be present at the same time, however) to make the diagnosis of SLE. If <=3 items are present, SLE is unlikely.
Using these criteria, both sensitivity and specificity are each 96% for diagnosis of SLE.
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