Anterior chamber cell and flare, increased IOP, hyphema, and possible iris TIDs. Usually secondary to irritation from a malpositioned anterior or posterior chamber intraocular lens with adjacent iris and ciliary body chafe. UBM may help to confirm diagnosis by demonstrating IOL haptic contact to ciliary body in the sulcus.

1. Atropine 1% b.i.d.
2. Topical steroid (e.g., prednisolone acetate 1% four to eight times per day or difluprednate 0.05% four to six times per day) and consider topical NSAID (e.g., ketorolac q.i.d., bromfenac b.i.d., or nepafenac daily).
3. Systemic CAI (e.g., acetazolamide 500 mg sequel p.o. b.i.d.) or may consider topical CAI (e.g., dorzolamide 2% t.i.d.).
4. Topical β-blocker (e.g., timolol 0.5% daily or b.i.d.) and α2 agonist (e.g., brimonidine 0.1% to 0.2% b.i.d. to t.i.d.).
5. Consider laser ablation if bleeding site can be identified.
6. Consider surgical repositioning, replacement, or removal of the intraocular lens, especially if patient experiences recurrent episodes, formation of PAS, or persistent CME.
7. Consider YAG vitreolysis if vitreous strands can be seen.