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Fortified Bacitracin (10,000 U/mL)
Add enough sterile water (without preservative) to 50,000 U bacitracin dry powder to form 5 mL of solution. This provides a concentration of 10,000 U/mL. Refrigerate. Expires after 7 days.
Fortified Cefazolin (50 mg/mL)
Add enough sterile water (without preservative) to 500 mg of cefazolin dry powder to form 10 mL of solution. This provides a strength of 50 mg/mL. Refrigerate. Expires after 7 days.
Fortified Ceftazidime (50 mg/mL)
Add 10 mL of sterile water to 1 g of ceftazidime. Draw up 7.5 mL of this solution and add it to a sterile dropper bottle. Then add 7.5 mL of sterile water to the dropper bottle to produce a concentration of 50 mg/mL. Refrigerate. Expires after 7 days.
Fortified Tobramycin (or Gentamicin) (15 mg/mL)
With a syringe, inject 2.4 mL of tobramycin, 40 mg/mL, directly into a 5-mL bottle of tobramycin, 0.3%, ophthalmic solution. This gives a 7-mL solution of fortified tobramycin (approximately 15 mg/mL). Refrigerate. Expires after 14 days.
Fortified Vancomycin (25 mg/mL)
Add enough sterile water (without preservative) to 500 mg of vancomycin dry powder to form 10 mL of solution. This provides a strength of 50 mg/mL. To achieve a 25-mg/mL concentration, take 5 mL of 50-mg/mL solution and add 5-mL sterile water. Refrigerate. Expires after 7 days.
Fortified Voriconazole (0.5 mg/mL)
Dilute 1 mL of IV voriconazole (10 mg/mL) with 19 mL of sterile water. This provides a strength of 0.5 mg/mL. Refrigerate. Expires after 7 days. Filter the solution prior to topical administration.