Multiple endocrine neoplasia (MEN) syndromes: incidence of tumor types. | ||||
| Tumor Type | MEN 1 | MEN 2 (MEN 2A) | MEN 3 (MEN 2B) | MEN 4 |
|---|---|---|---|---|
| Parathyroid | 95% | 20-50% | Rare | Common |
| Pancreatic | 54% | Common | ||
| Pituitary | 42% | Common | ||
| Medullary thyroid carcinoma | >90% | 80% | ||
| Pheochromocytoma | Rare | 20-35% | 60% | |
| Mucosal and GI ganglioneuromas | Rare | >90% | ||
| Subcutaneous lipoma | 30% | |||
| Adrenocortical adenoma | 30% | Common | ||
| Thoracic carcinoid | 15% | |||
| Thyroid adenoma | 55% | Common | ||
| Facial angiofibromas and collagenomas | 85% | |||
| Breast cancer | 27% | |||