Multiple endocrine neoplasia (MEN) syndromes: incidence of tumor types. | ||||
Tumor Type | MEN 1 | MEN 2 (MEN 2A) | MEN 3 (MEN 2B) | MEN 4 |
---|---|---|---|---|
Parathyroid | 95% | 20-50% | Rare | Common |
Pancreatic | 54% | Common | ||
Pituitary | 42% | Common | ||
Medullary thyroid carcinoma | >90% | 80% | ||
Pheochromocytoma | Rare | 20-35% | 60% | |
Mucosal and GI ganglioneuromas | Rare | >90% | ||
Subcutaneous lipoma | 30% | |||
Adrenocortical adenoma | 30% | Common | ||
Thoracic carcinoid | 15% | |||
Thyroid adenoma | 55% | Common | ||
Facial angiofibromas and collagenomas | 85% | |||
Breast cancer | 27% |