AHFS Class:

48:48.24 Phosphodiesterase type 5 inhibitors

Generic Name

• Sildenafil Citrate

Sildenafil citrate injection is available in single-use vials containing 10 mg of sildenafil in 12.5 mL.³⁷⁶⁴ Each mL of solution contains the equivalent of 0.8 mg of sildenafil as the citrate salt and dextrose in water for injection.³⁷⁶⁴

Equivalency

Sildenafil citrate 1.124 mg is equivalent to 0.8 mg of sildenafil.³⁷⁶⁴

Trade Name(s)

Revatio

Sildenafil citrate injection is administered by intravenous bolus injection.³⁷⁶⁴

Sildenafil citrate injection is a clear, colorless solution.³⁷⁶⁴ Intact vials should be stored at controlled room temperature.³⁷⁶⁴ Vials are for single use only; unused portions should be discarded.³⁷⁶⁴

Syringes

Sildenafil citrate (Revatio) diluted in dextrose 5% to a concentration of 0.067 or 0.667 mg/mL was stored in 50-mL polypropylene syringes (Plastipak, Becton Dickinson) at 20 to 25°C and 37°C for 7 days.³⁷⁶⁵ The drug was found to be stable with less than 5% loss in 7 days at either storage temperature.³⁷⁶⁵

Additive Compatibility

Y-Site Injection Compatibility (1:1 Mixture)

For a list of references cited in the text of this monograph, search the monograph titled References.

ASHP^® Injectable Drug Information^TM. Selected Revisions December 5, 2024. © Copyright, 2024. American Society of Health-System Pharmacists^®, 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.