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Information

AHFS Class:

76:00 Oxytocics

Generic Name

Products

Methylergonovine maleate is available as a 0.2-mg/mL injection solution in 1-mL single-dose vials.3299 Each mL of solution contains methylergonovine maleate 0.2 mg, maleic acid 0.1 mg, and sodium chloride 7 mg in water for injection.3299

pH

From 2.7 to 3.5.175

Trade Name(s)

Methergine

Administration

Methylergonovine maleate is administered intramuscularly.3299 The drug also may be administered intravenously slowly over no less than 1 minute, in combination with careful blood pressure monitoring, if intravenous administration is considered essential as a life-saving measure; it should not be administered routinely by the intravenous route.3299 Administration of methylergonovine maleate by intra-arterial or periarterial injection must be strictly avoided.3299

Stability

Methylergonovine maleate injection is a clear, colorless solution.3299 Intact vials should be stored under refrigeration at 2 to 8°C and protected from light.3299 The product should be inspected visually for particulate matter and discoloration prior to administration.3299

To prevent inadvertent administration to newborn infants, methylergonovine maleate should be stored separately from medications intended for neonatal administration.3299

Compatibility

Y-Site Injection Compatibility (1:1 Mixture)

Other Info

References

For a list of references cited in the text of this monograph, search the monograph titled References.

Copyrights

ASHP® Injectable Drug InformationTM. Selected Revisions December 20, 2025. © Copyright, 2025. American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.