Scopolamine hydrobromide is available as a 0.4- or 0.6-mg/mL injection solution in 1 mL single-dose vials or ampuls with hydrobromic acid for pH adjustment.4061; 4062 Sodium chloride also may be present.4062
Other formulations, concentrations, or packages sizes may be available.
Osmolality
The osmolality of scopolamine hydrobromide 0.5 mg/mL was determined to be 303 mOsm/kg.1233
Scopolamine hydrobromide may be administered by intramuscular, intravenous, or subcutaneous injection.4061; 4062
Intact containers be stored at controlled room temperature and protected from light.4061; 4062 Do not freeze.4061 Scopolamine hydrobromide decomposition is primarily due to hydrolysis below pH 3 and to both hydrolysis and inversion about the chiral carbon above pH 3. The minimum rate of decomposition occurs at pH 3.5.1072
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