AHFS Class:

90:24.20.92 Interleukin-mediated Agents, Miscellaneous

Anakinra is available as a solution in single-dose prefilled glass syringes containing 100 mg of drug in 0.67 mL of solution.²⁸⁵⁹ Each syringe containing 0.67 mL of solution also contains anhydrous citric acid 1.29 mg, sodium chloride 5.48 mg, disodium EDTA 0.12 mg, and 0.7 mg of polysorbate 80 in water for injection.²⁸⁵⁹

pH

6.5.²⁸⁵⁹

Trade Name(s)

Kineret

Anakinra is administered by subcutaneous injection.²⁸⁵⁹ Prefilled syringes should placed at room temperature for 30 minutes prior to administration.²⁸⁵⁹

Intact containers should be stored at 2 to 8°C.²⁸⁵⁹ Protect from light.²⁸⁵⁹ Do not freeze.²⁸⁵⁹ Do not shake.²⁸⁵⁹

Visually inspect the syringes prior to use.²⁸⁵⁹ The solution should be clear and colorless to white, and may contain trace amounts of small, translucent to white, amorphous protein particles.²⁸⁵⁹ If the number of these particles appears excessive or the solution is discolored, cloudy, or particulate matter is present, the syringe should be discarded.²⁸⁵⁹

Y-Site Injection Compatibility (1:1 Mixture)

For a list of references cited in the text of this monograph, search the monograph titled References.

ASHP^® Injectable Drug Information^TM. Selected Revisions June 30, 2026. © Copyright, 2026. American Society of Health-System Pharmacists^®, 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.