Aminocaproic acid is available as a 250-mg/mL concentrate for injection in 20-mL vials containing aminocaproic acid 5 g in water for injection and may contain hydrochloric acid and/or sodium hydroxide for pH adjustment.1360; 1361 Aminocaproic acid concentrate for injection is available with benzyl alcohol 0.9% as a preservative in multiple-dose vials and also in preservative-free form in single-dose vials.1360; 1361 The concentrate must be diluted prior to administration.1360; 1361
pH
Aminocaproic acid is administered by intravenous infusion after dilution in a compatible solution.1360; 1361 Rapid intravenous injection of the undiluted drug is not recommended.1360; 1361
Intact vials should be stored at controlled room temperature.1360; 1361
Standardize 4 Safety
One or more standardized concentrations for this drug have been established through Standardize 4 Safety (S4S), a national patient safety initiative to reduce medication errors, especially during transitions of care. (See Standardize 4 Safety in Users Guide.) Recommendations developed to date through this initiative are available at www.ashp.org/pharmacy-practice/standardize-4-safety-initiative.
Table 1. Standardize 4 Safety Continuous IV Infusion Standard Concentrations for Vasopressin3635
| Patient Population | Concentration Standards | Dosing Units |
|---|---|---|
| Pediatric patients (50 kg) | 20 mg/mL 100 mg/mL | mg/kg/hour |
For a list of references cited in the text of this monograph, search the monograph titled References.