Enalaprilat is available in 1- and 2-mL vials.3249 Each mL of solution contains enalaprilat 1.25 mg with sodium chloride to adjust tonicity and benzyl alcohol 9 mg in water for injection.3249 The solution also may contain sodium hydroxide to adjust the pH.3249
Enalaprilat is administered intravenously slowly over at least 5 minutes either undiluted or diluted with up to 50 mL of a compatible intravenous infusion solution.3249
Enalaprilat is a clear, colorless solution.3249 Intact vials should be stored at controlled room temperature.3249
Enalaprilat solution should be visually inspected for particulate matter and discoloration prior to administration.3249
Central Venous Catheter
Enalaprilat (Merck) 0.1 mg/mL in dextrose 5% was found to be compatible with the ARROWg+ard Blue Plus (Arrow International) chlorhexidine-bearing triple-lumen central catheter. Essentially complete delivery of the drug was found with little or no drug loss occurring. Furthermore, chlorhexidine delivered from the catheter remained at trace amounts with no substantial increase due to the delivery of the drug through the catheter.2335
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