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Footnotes

a Tested in dextrose 5%.

b Tested in sodium chloride 0.9%.

c Tested in both dextrose 5% and sodium chloride 0.9%.

d Tested in sterile water for injection.

e Sulbactam component. Sulbactam in a 1:1 fixed-ratio concentration with durlobactam.

f Concentration unspecified.

g Infused over one hour simultaneously with methotrexate.

h Tested with 0.1% albumin human added.

i Lyophilized formulation tested.

j Refer to Appendix for the composition of parenteral nutrition solutions. TNA indicates a 3-in-1 admixture, and TPN indicates a 2-in-1 admixture.

k Run at 21 mL/hr.

l Given over 30 minutes by syringe pump.

m Run at 94 mL/hr.

n Run at 10 mL/hr.

o Given over one hour by syringe pump.

p Tested in a 1:1 mixture of (1) dextrose 5% and dextrose 5% in sodium chloride 0.45% with and without potassium chloride 20 mEq/L and also in (2) dextrose 10% in sodium chloride 0.45% with and without potassium chloride 20 mEq/L.

q Tested with albumin human 0.1%.

r Test performed using the formulation WITHOUT edetate disodium.

s Tested in either dextrose 5% or in sodium chloride 0.9%, but the report did not specify which solution.

t Ampicillin component. Ampicillin in a 2:1 fixed-ratio concentration with sulbactam.

u Piperacillin component. Piperacillin in an 8:1 fixed-ratio concentration with tazobactam.

v Meropenem component. Meropenem in a 1:1 fixed-ratio concentration with vaborbactam.

w If sterile water for injection is used as the diluent, manufacturers recommend a maximum volume per dose of 50 mL.

x Ceftolozane component. Ceftolozane in a 2:1 fixed-ratio concentration with tazobactam.

y Run at 25 mL/hr with dextrose 5% run at 83 mL/hr.

z Run at 100 mL/hr.

aa Test performed using the formulation WITH edetate disodium.

bb Tested as the premixed infusion solution.

cc Ceftazidime component. Ceftazidime in a 4:1 fixed-ratio concentration with avibactam.

dd Salt not specified.

ee Presence or absence of edetate disodium not specified.

ff Not specified whether concentration refers to single component or combined components.

gg Imipenem component. Imipenem in a 2:2:1 fixed-ratio concentration with cilstatin and relebactam.

hh Subvisible particulate test methods include light obscuration, flow imaging microscopy, and backgrounded membrane imaging.