Butorphanol tartrate is available in concentrations of 1 mg/mL (in 1-mL vials) and 2 mg/mL (in 1- and 2-mL single-use vials and 10-mL multidose [preserved] vials).2904; 2905
Each mL of solution also contains citric acid 3.3 mg, sodium citrate 7.29 mg (equivalent to sodium citrate anhydrous 6.4 mg),2904 and sodium chloride 6.4 mg.2904; 2905 Also present in the multidose vials is 0.1 mg/mL of benzethonium chloride as a preservative.2904
pH
From 3 to 5.5.2904
Butorphanol tartrate injection should be stored at controlled room temperature and retained in the original carton to protect from light.2904; 2905
Central Venous Catheter
Butorphanol tartrate (Apothecon) 0.04 mg/mL in dextrose 5% was found to be compatible with the ARROWg+ard Blue Plus (Arrow International) chlorhexidine-bearing triple-lumen central catheter. Essentially complete delivery of the drug was found with little or no drug loss occurring. Furthermore, chlorhexidine delivered from the catheter remained at trace amounts with no substantial increase due to the delivery of the drug through the catheter.2335
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