28:24.92 Anxiolytics, Sedatives, and Hypnotics; Miscellaneous
Generic Name
Synonym
Methotrimeprazine hydrochloride injection is available as a 25-mg/mL solution in 1-mL ampuls.3823; 3824; 3825 The injection also contains ascorbic acid, sodium sulfite, and sodium chloride in water for injection.3823; 3824; 3825
pH
From 3 to 5.3826
Osmolality
Methotrimeprazine hydrochloride injection is an isotonic solution.3824
Trade Name(s)
Nozinan
Methotrimeprazine hydrochloride is administered by intramuscular injection or intravenously after dilution with an equal volume of sodium chloride 0.9% immediately before use.3823; 3824 Methotrimeprazine hydrochoride also may be administered by slow intravenous infusion (20 to 40 drops per minute) after dilution in 250 mL of dextrose 5%.3825
Methotrimeprazine hydrochloride also may be administered by continuous subcutaneous infusion diluted with the appropriate volume of sodium chloride 0.9%.3824
Methotrimeprazine hydrochloride injection is a clear, colorless solution.3823; 3824 Intact ampuls should be stored at room temperature and protected from light.3823; 3824; 3825 Some manufacturers specify a storage temperature of below 25°C3824 or 15 to 30°C.3825 On exposure to light, methotrimeprazine hydrochloride rapidly develops a pink or yellow discoloration; discolored solutions should be discarded.3824
Methotrimeprazine hydrochloride injection is incompatible with alkaline solutions.3823; 3824
For a list of references cited in the text of this monograph, search the monograph titled References.