b Tested in sodium chloride 0.9%.
c Tested in both dextrose 5% and sodium chloride 0.9%.
d Tested in dextrose 5%, sodium chloride 0.9%, and Ringers injection, lactated.
e Lyophilized formulation tested.
f Refer to Appendix for the composition of parenteral nutrition solutions. TNA indicates a 3-in-1 admixture, and TPN indicates a 2-in-1 admixture.
g A 32.5-mL sample of parenteral nutrition solution mixed with 50 mL of antibiotic solution.
i Given over five minutes by syringe pump.
k Tested in sterile water for injection.
l Test performed using the formulation WITHOUT edetate disodium.
m Tested in either dextrose 5% or in sodium chloride 0.9%, but the report did not specify which solution.
n Tested in a 1:1 mixture of (1) dextrose 5% and dextrose 5% in sodium chloride 0.45% with and without potassium chloride 20 mEq/L and also in (2) dextrose 10% in sodium chloride 0.45% with and without potassium chloride 20 mEq/L.
o Tested in combination with hydrocortisone sodium succinate (Upjohn) 100 mg/L
p Tested in combination with heparin sodium (Rikers) 1000 units/L
q Test performed using the formulation WITH edetate disodium.
r Subvisible particulate test methods include light obscuration, flow imaging microscopy, and backgrounded membrane imaging.