Bone and Soft-Tissue Disorders
= mesenchymal tumor of fibroblastic / myofibroblastic origin and intermediate malignant potential
- Clinical behavior + histopathologic features are similar to hemangiopericytoma
- Most solitary fibrous tumors are benign!
Histo: patternless architecture characterized by alternating hypo- and hypercellular areas separated by thick bands of hyalinized collagen and branching vessels
Age: middle-aged adults
Location: anywhere; extrapleural >pleural site
- head & neck: nasal cavity, paranasal sinus, nasopharynx, parapharyngeal space, larynx
- meninges
May be associated with: hypoglycemia (← overproduction of insulinlike growth factor), arthralgia, osteoarthropathy, digital clubbing
- slow-growing mass ± local mass effect
CT:
- solitary well-circumscribed lobulated mass
- soft-tissue attenuation
- intense contrast enhancement
- heterogeneous texture if large ← hemorrhage, necrosis, cysts
MR:
- well-circumscribed solid mass
- low to intermediate SI on T1WI + T2WI
- heterogeneously high SI on T2WI ← myxoid / cystic degeneration
- low signal-intensity rim around lesion (= pseudocapsule) on T2WI
- hypervascularity with prominent enhancement + flow voids
DDx: hemangiopericytoma (overlapping histology)