Bone and Soft-Tissue Disorders
= excessive ingestion of vitamin D (large doses act like parathormone)
- loss of appetite, diarrhea, drowsiness, headaches
- polyuria, polydipsia, renal damage; convulsions
- excessive phosphaturia (parathormone decreases tubular absorption); hypercalcemia + hypercalciuria; anemia
- deossification
- widening of provisional zone of calcification
- cortical + trabecular thickening
- alternating bands of increased + decreased density near / in epiphysis (zone of provisional calcification)
- vertebra outlined by dense band of bone + adjacent radiolucent line within
- dense calvarium
- metastatic calcinosis in
- arterial walls (between age 20 and 30 years)
- kidneys = nephrocalcinosis
- periarticular tissue (puttylike)
- premature calcification of falx cerebri (most consistent sign!)