Nervous System Disorders
= PSEUDOTUMOR CEREBRI = BENIGN INTRACRANIAL HYPERTENSION (BIH)
Pathophysiology:
- elevation in blood volume (85%)
- decrease in regional cerebral blood flow with delayed CSF absorption (10%)
Etiology:
- Sinovenous occlusive disease, SVC occlusion, obstruction of dural sinus, obstruction of both internal jugular veins
- Dural AVM
- S/P brain biopsy with edema
- Endocrinopathies
- Hypervitaminosis A
- Hypocalcemia
- Menstrual dysfunction, pregnancy, menarche, birth control pills
- Drug therapy
Predilection for: obese young to middle-aged women
- headache
- papilledema
- elevated opening pressures on lumbar puncture (normal range of 80180 mm H2O in horizontal lateral decubitus position)
- normal ventricular size / pinched ventricles
- increased volume of subarachnoid space