Skull and Spine Disorders
= subset of meningeal cysts
Cause: posttraumatic, postinfectious, congenital diverticulum, idiopathic (arachnoid herniation through dural defect /abnormal distribution of arachnoid trabeculations)
Histo: lined with fibrous tissue + scattered meningothelial cells
Age: 1545 years (in 77%); range of several months to 80 years; M=F
Relationship to CSF:
- encapsulated completely separate from CSF
- communication with subarachnoid space via a neck ± one-way valve
- pain (waxing + waning), sensory changes, urinary dysfunction, weakness
- progressive spastic / flaccid paresis improving in supine position + worsening during Valsalva maneuver
- symptomatic with compression of spinal cord / nerve root ← arachnoid cyst expansion (osmotic gradient, ball-valve mechanism, active secretions from cyst lining)
- oval sharply demarcated extramedullary mass
- filling with intrathecal contrast material depending upon size of opening between cyst + subarachnoid space:
initially in 50%, nearly 100% with delayed imaging
DDx: epidermoid cyst (asymmetric filling defect) - local displacement + compression of spinal cord
- higher SI than CSF (from relative lack of CSF pulsations)
- NO enhancement
MR:
- iso- to hyperintense to CSF on T1WI + T2WI
- variability in signal intensity ← pulsatility of CSF / higher protein content
- isointense to CSF on FLAIR MR images
- NO restricted diffusion at DWI
Types:
- I extradural arachnoid cyst without nerve root fibers
- Ia extradural arachnoid cyst
- Ib sacral meningocele
- II extradural meningeal cyst containing neural tissue (= Tarlov cyst)
- III intradural arachnoid cyst
Pitfalls of CT myelography / MRI:
- Nonopacification of noncommunicating arachnoid cyst → misidentification as a different type of lesion
- Absence of mass effect on cord → failure to detect additional cysts / small CSF-isointense arachnoid cyst
DDx: traumatic / lateral thoracic meningoceles
Cx: spinal cord myelopathy, nerve root radiculopathy
Extradural Arachnoid Cyst
Cause: congenital / acquired dural defect
Age: 2nd decade of life; M>F
Location: thoracic (80%) >cervical (15%) >lumbar (5%)spine; extending over 3.7 vertebral bodies
Site: posteriorly / posterolaterally to cord
- scalloping of vertebral body
- thinning / erosion of pedicles
- widening of interpeduncular distance
Intradural Arachnoid Cyst
Cause: congenital deficiency within arachnoid (= true arachnoid cyst) / adhesion from prior infection or trauma (= arachnoid loculation)
- focal displacement and compression of spinal cord
- widened dorsal subarachnoid space with diminished CSF flow artifact
Outline