Bone and Soft-Tissue Disorders
= developmental abnormality classified as benign bone tumor
Prevalence: 3035% of children; M÷F = 2÷1
Peak age: 78 (range, 220) years; mostly before epiphyseal closure
Histo: fibrous tissue from periosteum invading underlying cortex
- asymptomatic, usually incidental finding
In 5% associated with: neurofibromatosis
Location: metaphyseal cortex of long bone (near physis); multiple locations bilateral + symmetric in 50%
- femur (40%): posterior medial aspect of distal femur, proximal femur
- tibia (40%): proximal tibia
- fibula (10%)
- others: proximal humerus, ribs, ilium
Size:<2 cm in largest diameter
Early stage:
- circular / oval eccentrically located radiolucent area extending parallel to long axis of host bone
- smooth lobulated / scalloped margins with well-defined thin rim of sclerosis
- no periosteal reaction
- high SI on T2WI (cystic component early stage) + low SI on T1WI
- little / no uptake on bone scintigraphy
Late stage:
- low SI on T2WI (progressive sclerosis + ossification) and on T1WI
- sclerotic bone island (may be residue of incompletely involuted cortical defect in the adult)
Prognosis:
- involution over 24 years
- potential to grow and encroach on the medullary cavity leading to nonossifying fibroma (defined as >2 cm in size)
DDx: Nonossifying fibroma