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Information

 Bone and Soft-Tissue Disorders

= developmental abnormality classified as benign bone tumor

Prevalence: 30–35% of children; M÷F = 2÷1

Peak age: 7–8 (range, 2–20) years; mostly before epiphyseal closure

Histo: fibrous tissue from periosteum invading underlying cortex

In 5% associated with: neurofibromatosis

Location: metaphyseal cortex of long bone (near physis); multiple locations bilateral + symmetric in 50%

  1. femur (40%): posterior medial aspect of distal femur, proximal femur
  2. tibia (40%): proximal tibia
  3. fibula (10%)
  4. others: proximal humerus, ribs, ilium

Size:<2 cm in largest diameter

Early stage:

Late stage:

Prognosis:

  1. involution over 2–4 years
  2. potential to grow and encroach on the medullary cavity leading to nonossifying fibroma (defined as >2 cm in size)

DDx: Nonossifying fibroma