Bone and Soft-Tissue Disorders
= VOORHOEVE DISEASE
= disorder of secondary spongiosa of X-linked dominant inheritance / sporadic occurrence
- usually asymptomatic (similar to osteopoikilosis)
- NO known associated physical / laboratory abnormality → incidental radiographic discovery
Genetics: unknown
Location: all long bones symmetrically affected
Site: the only bone sclerosis primarily involving metaphysis (with extension into epi- and diaphysis)
- dense linear longitudinal striations in diaphyses + metaphysis of long tubular bones: typically in areas of rapid growth
- radiating fan-shaped densities of sunburst appearance from acetabulum into ileum