| Bilirubin Overload (Hemolysis) | Parenchymal Dysfunction | Cholestasis | |
|---|---|---|---|
| Aminotransferases | Normal | Increased (may be normal or decreased in advanced stages) | Normal (may be increased in advanced stages) |
| Alkaline phosphatase | Normal | Normal | Increased |
| Bilirubin | Increased unconjugated | Increased conjugated | Increased conjugated |
| Serum proteins | Normal | Decreased | Normal (may be decreased in advanced stages) |
| Prothrombin time | Normal | Decreased (may be normal in early stages) | Normal (may be prolonged in advanced stages) |
| Blood urea nitrogen | Normal | Normal (may be decreased in advanced stages) | Normal |
| Sulfobromophthalein/indocyanine green | Normal | Retention | Normal or retention |