• Use Fio ₂ of 1.0.
• Ventilate with a tidal volume of 6–8 mL/kg with PEEP 5 cm H₂O.
• Respiratory rate to maintain PaCO₂ between 35 and 45 mm Hg.
• Check the DLT position subsequent to lateral decubitus positioning.
• If peak airway pressure >40 mm Hg during OLV, malposition of the double-lumen tube must be considered.
• For arterial hypoxemia, apply CPAP 10 cm H₂O to the nondependent lung (not during video-assisted thoracoscopy).
• If additional correction of arterial hypoxemia is necessary, add PEEP 5–10 cm H₂O to the ventilated lung.
• Frequent recruiting maneuvers.
• Avoid fluid overload.
• TIVA may be preferable to inhalation anesthetics.
• If necessary, intermittently inflate and deflate the operated lung.

CPAP= continuous positive airway pressure; DLT = double lumen tube; Fio ₂ = fraction of inspired oxygen; IV = intravenous; OLV= one-lung ventilation; PEEP = positive end-expiratory pressure; TIVA = total intravenous anesthetic.