- Increased cerebral perfusion and intracranial pressure
- Caution in patient with brain tumor or ventriculoperitoneal shunt
- Decreased splanchnic blood flow
- Decreased or no change in bowel perfusion (mechanical pneumoperitoneum compression balanced by hypercarbic vasodilation)
- Decreased hepatic blood flow (beneficial during cryoablation of liver metastasis)
- Reduced renal perfusion and urine output (reduced during pneumoperitoneum with recovery after deflation)
- Decreased femoral vein flow
- Increased potential for deep vein thrombosis and pulmonary embolism
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