Preparing to manage, deal with the sequelae of, and mitigate future disasters originating from natural events, industrial accidents, or of more interest recently, caused intentionally by terrorists using chemical, biologic, radiologic, nuclear, or high-yield explosive (CBRNE) agents is a high priority for the majority of governments the world over (Murray MJ. Emergency preparedness for and disaster management of casualties from natural disasters and chemical, biologic, radiologic, nuclear, and high-yield explosive (CBRNE) events. In: Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Ortega R, Stock MC, eds.Clinical Anesthesia. Philadelphia: Lippincott Williams & Wilkins; 2013:1535–1552) (Table 53-1: Examples of Chemical, Biologic, Radiologic, Nuclear, and High-Yield Explosive Events). The American Society of Anesthesiologists has recognized the importance of such activities and in the past decade has established a Committee on Emergency Preparedness and Trauma and a Global Health Initiative. Certain principles are common to all such events independent of their etiology, and as a group, anesthesiologists are as well prepared if not better prepared to assist their communities in planning for and in caring for patients from a disaster.