| Drug | Relative β 1 Selectivity | Membrane Stabilizing Activity | Intrinsic Sympathomimetic Activity | Elimination Half-Time (hr) | Lipid Solubility | Route of Elimination |
|---|---|---|---|---|---|---|
| Propranolol | 0 | + | 0 | 3–4 | +++ | Hepatic |
| Metoprolol | ++ | 0 | 0 | 3–4 | + | Hepatic |
| Atenolol | ++ | 0 | 0 | 6–9 | 0 | Renal |
| Esmolol | ++ | 0 | 0 | 0.16 | ? | Plasma esterase |
| Timolol | 0 | 0 | 0 | 4–5 | + | Hepatic Renal |