Anesthetic drugs are administered with the goal of rapidly establishing and maintaining a therapeutic effect while minimizing undesired side effects (Gupta DK, Henthorn TK. Basic principles of clinical pharmacology. In: Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Ortega R, Stock MC, eds.Clinical Anesthesia. Philadelphia: Lippincott Williams & Wilkins; 2013: 156188).